@article{reshef2018detecting,
  title={Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk},
  author={Reshef, Yakir A and Finucane, Hilary K and Kelley, David R and Gusev, Alexander and Kotliar, Dylan and Ulirsch, Jacob C and Hormozdiari, Farhad and Nasser, Joseph and O’Connor, Luke and Van De Geijn, Bryce and others},
  journal={Nature genetics},
  volume={50},
  number={10},
  pages={1483--1493},
  year={2018},
  publisher={Nature Publishing Group}
}